生物原纳米颗粒的内生体介导生物合成:机制和生物医学应用
Mariyam Zama Shariff1,2, Dhanush Govinakere Mallegowda1,2, Raghu Ningegowda3
1Centre for Research and Innovation, Adichunchanagiri University, B.G. Nagara, Mandya, Karnataka, 571448, India.
Archives of microbiology
|January 6, 2026
概括
在植物中生活的微生物内菌被用来制造具有增强抗微生物和抗癌特性的纳米粒子. 需要进一步的研究来了解它们的机制,并确保现实世界的应用程序的安全.
科学领域:
- 生物技术和纳米科学 生物技术和纳米科学
- 微生物学 微生物学
- 材料科学 材料科学 材料科学
背景情况:
- 内菌是居住在植物组织中的微生物,不会引起疾病.
- 它们产生具有多种治疗性质的生物活性代谢物.
- 内植物作为天然工厂,用于纳米粒子的绿色合成.
研究的目的:
- 为了回顾过去十年对内细胞介导纳米粒子合成的研究.
- 批判性地评估这些纳米粒子的表征和应用.
- 识别知识缺口和未来的研究方向.
主要方法:
- 主要科学数据库的系统文献搜索.
- 包括关于生物医学,农业和环境应用的同行评审文章.
- 不包括缺乏机械或功能数据的描述性报告.
主要成果:
- 源自内菌的纳米颗粒显示出增强的生物活性,包括抗微生物和抗癌作用.
- 在农业中的应用包括改善营养吸收和耐压力.
- 在机械学理解,植物毒性和可扩展性方面存在重大知识差距.
结论:
- 以内生植物为媒介的纳米技术为全球健康和粮食安全提供了一个可持续的平台.
- 跨学科的研究,监管的明确性和毒理学评估对于翻译至关重要.
- 为了进步,需要标准化的协议和基于omics的洞察力.
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