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Updated: Jan 13, 2026

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
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Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter

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ZMYM3 S464:在表观遗传重塑和瘤发生过程中,一个潜在的调节枢纽

Apoorva Pai1, Althaf Mahin1, Samseera Ummar1

  • 1Centre for Integrative Omics Data Science, Yenepoya (Deemed to be University), Mangalore, Karnataka, 575018, India.

Molecular genetics and genomics : MGG
|January 6, 2026
PubMed
概括

在S464中ZMYM3蛋白酸化是DNA修复和表观遗传沉默的关键调节者. 这个网站这个网站.

关键词:
细胞骨组织组织癌症表观遗传学 癌症表观遗传学在中国,有中国人.基蛋白质组是基蛋白质组的组成部分.在 ZMYM3 里面,你会看到 ZMYM3.

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Epigenetic Regulation01:37

Epigenetic Regulation

Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
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Master transcription regulators are regulatory proteins that are predominantly responsible for regulating the expression of multiple genes. Often these genes work in concert to drive a  complex process. Activation of a master transcription regulator can lead to a cascade of transcriptional activation necessary for that outcome. These regulators can directly bind to the regulatory sequences of the various genes involved, or they can indirectly regulate transcription by binding to regulatory...
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