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Updated: Jan 13, 2026

Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation
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Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation

Published on: January 19, 2019

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将抗体合物与细胞毒性和免疫刺激有效载荷相结合,最大限度地提高了抗癌活性

Tiexin Wang1,2, Dong Jun Koo1, Peter M Tessier1,2,3,4,5

  • 1Department of Chemical Engineering, University of Michigan, Ann Arbor, USA.

Molecular oncology
|January 6, 2026
PubMed
概括

结合抗体-药物合物 (ADC) 与免疫刺激抗体合物 (ISAC) 有效地治疗瘤,甚至是免疫冷的瘤. 这种组合疗法提高了疗效和耐久性,提供了一个有前途的新癌症治疗策略.

关键词:
这是一个ADCADC ADC.在 CEA CEA 中.美国国际安全委员会 (ISAC)刺痛激动剂 刺痛激动剂 刺痛激动剂抗体药物合物 抗体药物合物免疫刺激抗体结合的结合体.

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