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揭开前列腺癌中的微生物景观:从发病到治疗

Xiancai Du¹, Jing Wu¹, Siyuan Xia²

¹Department of Human Cell Biology and Genetics, School of Medicine and SUSTech Homeostatic Medicine Institute (SHMI), Southern University of Science and Technology, Shenzhen, Guangdong, China.

NPJ biofilms and microbiomes

|January 6, 2026

概括

肠道微生物组影响前列腺癌的发展和治疗反应. 本综述探讨了各种微生物如何影响前列腺癌,指导未来基于微生物的治疗方法.

科学领域:

微生物学微生物学
在瘤学瘤学.
胃肠病学胃肠病学

背景情况:

新出现的证据将微生物群与前列腺癌联系起来.
微生物在前列腺癌中的确切作用尚不清楚.

研究的目的:

系统地审查微生物群在前列腺癌中的作用.
要总结微生物如何影响前列腺癌的发病,进展和治疗.
为了确定开发基于微生物的治疗方法的知识差距.

主要方法:

系统检查皮肤,口腔,肠道,尿道和前列腺中的微生物.
对宿主微生物群相互作用中的分子通路和代谢重编程的分析.

主要成果:

来自各种身体部位的微生物群与前列腺癌有关.
特定的微生物群落影响癌症的发病和进展.
主体微生物群相互作用会影响治疗反应.

结论:

微生物群在前列腺癌中起着重要作用.
了解这些相互作用对于开发新的治疗策略至关重要.
需要进一步的研究来阐明具体的机制和指导临床应用.

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