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相关概念视频

Nucleic Acid Structure01:25

Nucleic Acid Structure

8.4K
The pentose sugar in DNA is deoxyribose, while in RNA the pentose sugar is ribose. The difference between the sugars is the presence of the hydroxyl group on the ribose's second carbon and a hydrogen on the deoxyribose's second carbon. The phosphate residue attaches to the hydroxyl group of the 5′ carbon of one sugar and the hydroxyl group of the 3′ carbon of the sugar of the next nucleotide, which forms  a 5′ to 3′ phosphodiester linkage.
DNA Structure
DNA...
8.4K
Nucleic acids02:43

Nucleic acids

188.2K
Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes,...
188.2K
Nucleic Acids02:43

Nucleic Acids

8.8K
8.8K
Nucleic Acids02:43

Nucleic Acids

49.5K
Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes,...
49.5K
Nucleic Acids and Nucleotides01:20

Nucleic Acids and Nucleotides

13.8K
Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and have instructions for its functioning. The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA).
Deoxyribonucleic Acid (DNA)
DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and the organelles such as chloroplasts and mitochondria....
13.8K
Molecular Models02:00

Molecular Models

43.5K
Physical models representing molecular architectures of chemical compounds play essential roles in understanding chemistry. The use of molecular models makes it easier to visualize the structures and shapes of atoms and molecules.
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相关实验视频

Updated: Jan 13, 2026

Analyzing and Building Nucleic Acid Structures with 3DNA
16:24

Analyzing and Building Nucleic Acid Structures with 3DNA

Published on: April 26, 2013

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DNATCO v5.0:用于3D核酸结构分析的综合网络平台.

Jiří Černý1, Michal Malý1, Paulína Božíková1

  • 1Institute of Biotechnology of the Czech Academy of Sciences, Průmyslová 595, Vestec 25250, Czech Republic.

Nucleic acids research
|January 7, 2026
PubMed
概括

DNATCO v5.0 是一种用于分析RNA和DNA结构的新网络工具. 它提供核酸模型的准确验证和改进,为所有用户改善生物解释.

科学领域:

  • 结构生物学 结构生物学
  • 生物信息学是一种生物信息学.
  • 计算化学的计算化学

背景情况:

  • 越来越复杂的RNA和DNA结构需要先进的分析工具.
  • 对核酸结构的准确解释,验证和改进对于生物学洞察至关重要.

研究的目的:

  • 介绍DNATCO v5.0,一个互动的网络应用程序,用于核酸的全面结构分析.
  • 提供一个整合二核酸构造类和结构字母表的工具,用于详细的几何描述.
  • 为了使核酸结构的定量验证与既定的几何标准相比.

主要方法:

  • 整合NtC二核酸构造类和CANA结构字母.
  • 使用confal分数和电子密度匹配和几何相似性的散射图进行定量验证.
  • 通过WebAssembly实现客户端实现,以实现快速性能和数据隐私.
  • 支持PDB和用户提供的结构模型.

主要成果:

  • DNATCO v5.0提供了直观的,在几何上完整的局部骨干和基础方向的描述.
  • 该平台对形状相似性,结合长度和角度进行定量验证.
  • 诊断工具有助于识别有问题的区域,并探索替代形状.

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相关实验视频

Last Updated: Jan 13, 2026

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16:24

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Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
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Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

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Design and Synthesis of a Reconfigurable DNA Accordion Rack
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Design and Synthesis of a Reconfigurable DNA Accordion Rack

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结论:

  • DNATCO v5.0 增强了对核酸结构进行自信评估的能力.
  • 该工具支持模型改进,为专家和非专家提供准确的生物解释.
  • WebAssembly的实施确保了核酸结构的高效和私有分析.