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Updated: Jun 26, 2026

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
14:57

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology

Published on: March 23, 2011

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空间和单细胞特征的综合分析揭示了细胞类型特定的调节突触可塑性在人类大脑衰老

Jingjing Guan1, Tiangang Wang1,2, Yu Zhou1

  • 1School of Life Science and Technology, Xidian University, No. 266 Xinglong Section of Xifeng Road, Chang'an District, Xi'an, Shaanxi 710126, China.

Human molecular genetics
|January 7, 2026
PubMed
概括

衰老会影响大脑功能,特别是前额叶皮层 (PFC). 这项研究揭示了刺激神经元中的EGR1功能障碍有助于与年龄相关的认知衰退和突触缺陷.

关键词:
大脑衰老的老化多个omics的多个omics.神经可塑性 神经可塑性单细胞转录组学 单细胞转录组学空间转录组学 空间转录组学

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