儿童喘肠道微生物群研究中的不断变化的景观:从2000年到2024年的文献分析分析
Yang Zhao1, Hongman Wang2, Yanxin Lu3
1The Fifth Affiliated Hospital of Zunyi Medical University (Zhuhai), Zhuhai, Guangdong Province, China.
Medicine
|January 7, 2026
概括
全球关于儿科喘和肠道微生物群的研究正在迅速扩大,揭示了诸如失生症和免疫机制等关键主题. 未来的工作重点是了解因果途径,并开发针对性治疗来个性化治疗喘.
科学领域:
- 儿科研究的研究.
- 微生物组科学 微生物组科学
- 免疫学 免疫学 免疫学
背景情况:
- 儿童喘与肠道微生物群失衡有关,影响免疫反应和炎症.
- 肠肺轴假设是理解这种复杂关系的核心.
- 多omics技术正在推动该领域的研究.
研究的目的:
- 分析儿童喘和肠道微生物群的全球研究趋势.
- 绘制协作网络的地图,并确定关键贡献者.
- 确定新兴的研究方向和主题.
主要方法:
- 从Web of Science核心集合中对635篇出版物 (2000-2024) 的图书统计分析.
- 使用CiteSpace和VOSviewer进行数据分析.
- 专注于与喘,儿童和肠道微生物群相关的关键词.
主要成果:
- 出版物的显著增长,特别是从2018年到2022年.
- 美国在生产率方面领先;加拿大拥有最高的引用影响.
- 关键主题包括肠道失调,短链脂肪酸 (SCFA),免疫失衡和早期暴露.
结论:
- 研究正在转向机理学研究和针对微生物群的治疗方法.
- 未来的研究应该优先考虑纵向队列和多学科融合.
- 跨学科研究对于个性化的儿科喘管理至关重要.
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