基于微生物-肠-大脑轴理论的针治疗失眠:一篇综述
1Heilongjiang University of Chinese Medicine, Harbin, China.
Medicine
|January 7, 2026
概括
针可以通过影响肠道微生物群及其与大脑的连接来治疗失眠. 本综述探讨了针如何影响微生物组-肠-大脑轴以缓解睡眠障碍.
科学领域:
- 综合医学是一个整体的医学.
- 神经科学是一个神经科学.
- 微生物学 微生物学
背景情况:
- 失眠严重影响生活质量和社会功能.
- 针是一种补充疗法,在治疗失眠方面越来越受到关注.
- 针治疗失眠的机制尚未完全理解,这促使人们对微生物组-肠-大脑轴进行研究.
研究的目的:
- 通过微生物组-肠-大脑轴探索针在改善失眠方面的潜在机制.
- 为针在失眠管理中的使用提供客观基础.
主要方法:
- 文献综述侧重于研究针,失眠和微生物群-肠-大脑轴.
- 分析拟议的途径,包括微生物组合,短链脂肪酸,炎症,肠道屏障功能,肠道,HPA轴和迷走神经.
主要成果:
- 针可以调节肠道微生物群的多样性和组成.
- 潜在的机制包括改变短链脂肪酸水平,减少炎症和增强肠道屏障完整性.
- 针可以影响脑肠的释放,并调节下丘脑-垂体-上腺轴和迷走神经通路.
结论:
- 针在治疗失眠方面表现有前途,通过准微生物组-肠道-大脑轴.
- 进一步的研究可以阐明这些机制,以基于证据的临床应用.
- 这些发现支持针作为治疗失眠的潜在治疗选择.
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