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Updated: May 6, 2026

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大脑脊髓液代谢物和多发性硬化症:一个双样本的门德尔随机化研究.

Dejin Zhang1,2, Jiaojiao Feng1, Jing Feng1

  • 1Department of Pharmacy, The People's Hospital of Linshui, Guangan, China.

Medicine
|January 7, 2026
PubMed
概括

大脑脊髓液 (CSF) 的代谢物显示出与多发性硬化症 (MS) 的因果关系. 特定的代谢物可能会增加MS风险,而其他代谢物可能会降低MS风险,提供潜在的预防目标.

关键词:
门德尔的随机化有关因果关系的因果关系大脑脊髓液的代谢物.全基因组关联研究研究.多发性硬化症多发性硬化症

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Multiple Sclerosis l: Introduction01:19

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Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
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