HbA1c调解了口功能和高血压之间的关联结果来自NHANES:一项观察性研究
1Department of Cardiology, Zhuji Affiliated Hospital of WenZhou Medical University, Shaoxing, Zhejiang Province, China.
Medicine
|January 7, 2026
概括
用功能性牙单位 (FTU) 衡量的良好的功能与较低的高血压风险有关. 这可能是由糖化血红蛋白水平调节的,特别是在某些年龄和性别群体.
科学领域:
- 公共卫生 公共卫生
- 牙科医学 牙科医学
- 心血管健康 心血管健康
背景情况:
- 高血压是全球主要的健康问题.
- 以前的研究表明,牙脱落和高血压之间存在联系.
- 功能在高血压风险中的具体作用,用功能牙单位 (FTU) 量化,尚不清楚.
研究的目的:
- 为了研究功能 (FTUs) 和高血压之间的关联.
- 探索这种关系中的潜在调解途径和效果修饰剂.
主要方法:
- 国家健康和营养检查调查 (NHANES) 数据 (2005-2018) 的分析.
- 通过问卷和血压测量来评估高血压.
- 功能是由功能性牙单位 (FTU) 定义的.
- 使用了后勤回归,受限立方线,子组和调解分析.
主要成果:
- 最佳的功能 (1012 FTU) 与18%的高血压风险降低有关 (OR 0.82,95% CI:0.720.92).
- 糖化血红蛋白被确定为一个显著的调解剂,解释了18.0%的总效果.
- 观察到FTU与高血压风险之间的非线性,反转的U形关联.
- 性别和年龄显著改变了FTUs-高血压关系.
结论:
- 更高的功能牙单元可能会降低高血压风险.
- 代谢标记物糖化血红蛋白似乎是一个关键的调解者.
- 研究结果强调了口功能在心血管健康中的重要性,并提出了潜在的干预目标.
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