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延长释放注射类 olanzapine (TV-44749) 在成年精神分裂症患者的第三阶段临床试验中用于皮下使用的基于人口药理学模型的剂量选择

Itay Perlstein1, Irina Cherniakov2, Anna Elgart2

  • 1Magic Wand Research LLC, Philadelphia, PA, USA.

Journal of clinical pharmacology
|January 7, 2026
PubMed
概括

一个新的皮下 olanzapine 注射 (TV-44749) 显示与口服 olanzapine 的暴露相当. 这种长效的注射配方旨在通过避免注射后痴呆症/镇静综合征来改善患者的治疗结果.

关键词:
选择剂量选择剂量选择长效注射剂 (LAI) 是一种长效注射剂.这种药物是 olanzapine.人口的药理动力学在皮下注射 olanzapine.

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