视觉脂肪作为骨瘤代谢风险因素:来自NHANES人口研究的见解
Xianliang Wang1, Rengcheng Qian2, Zhenlang Lin2
1Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
概括
通过年龄调整的内脏脂肪指数 (AVAI) 测量较高的内脏脂肪,与患骨瘤的风险增加有关. 这凸显了评估内脏脂肪对骨瘤风险的重要性.
科学领域:
- 在瘤学瘤学.
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 骨瘤是一种具有高死亡率的侵袭性恶性瘤.
- 肥胖导致癌症,包括骨瘤,通过内分泌失衡和炎症.
- 年龄调整的内脏脂肪指数 (AVAI) 提供了比BMI更好的肥胖风险评估.
研究的目的:
- 为了研究年龄调整的内脏脂肪指数 (AVAI) 和骨瘤发生之间的关联.
- 评估内脏脂肪是否是骨瘤的危险因素.
主要方法:
- 从2011-2018年NHANES数据对3731名成年人的横截面分析.
- 使用BMI,腰围,年龄,HDL和甘油三来计算AVAI.
- 对混因素调整后的逻辑回归评估了与AVAI四分位数相关的骨瘤风险.
主要成果:
- 骨瘤的患病率在较高的AVAI四分位数中增加,在最高四分位数中达到4.07%.
- 较高的AVAI与骨瘤风险增加显著相关 (OR=1.19).
- 调整后的分析显示,在较高的AVAI四分位数中,骨瘤的风险显著增加 (aORs从1.64到2.81).
结论:
- 在AVAI和骨瘤发育之间存在显著的关联.
- 对内脏脂肪的评估对于评估骨瘤风险至关重要.
- 进一步的研究应该探索针对与肥胖相关的骨瘤风险的机制和干预措施.
更多相关视频
07:00Dual Effects of Melanoma Cell-derived Factors on Bone Marrow Adipocytes Differentiation
Published on: August 23, 2018
6.5K
06:22Isolation of Viable Adipocytes and Stromal Vascular Fraction from Human Visceral Adipose Tissue Suitable for RNA Analysis and Macrophage Phenotyping
Published on: October 27, 2020
4.6K
相关概念视频
Obesity
1.1K
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
1.1K
Hormones and Bone Tissue
3.7K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
3.7K
Cholesterol: Significance and Regulation
1.2K
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Considering cholesterol and...
1.2K
