通过向MYC/ABCF1轴,NTRK2促进肺腺癌的恶性进展和帕克利塔塞尔耐药性

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Rongrong Cui1, Yuanyuan Wang1, Yao Yao1

  • 1Department of Endocrinology and International Joint Research Center for Tumor Precision Medicine of Shaanxi Province, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.

Translational oncology
|January 7, 2026
PubMed
概括

通过激活NTRK2/MYC/ABCF1通路,神经营养受体氨酸激酶2 (NTRK2) 驱动肺腺癌 (LUAD) 的进展和帕克利塔塞尔耐药性. 向NTRK2可能会在LUAD患者中克服化学抵抗.

关键词:
在ABCF1中,ABCF1是ABCF1.肺部腺癌瘤是肺部腺癌.我的世界 MYC这就是NTRK2的原因.帕克利塔克塞尔 (Paclitaxel) 是一种药物.

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