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Updated: Jan 13, 2026

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods
07:49

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods

Published on: July 17, 2019

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低RAF丰度对EGFR-ERK信号的系统级影响

Sung Hyun Lee1, Paul J Myers1, Max C Mendrzycki1

  • 1Department of Chemical Engineering.

Biophysical journal
|January 7, 2026
PubMed
概括

癌细胞中的低RAF丰度会造成信号瓶,可能影响ERK通路激活和耐药性. 计算模型揭示了 RAF 随机动态影响信号传播的动态.

关键词:
这是一种RAS突变.松散性分析的分析计算建模计算建模皮肤上生长因子受体.参数的灵敏度是指参数的灵敏度.随机模拟的随机模拟.

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