在Staphylococcus spp. 中,排泄相关的抗菌耐药性基因. 来自乳制品和肉类样本的样本
Meryem Burcu Külahci1, Sumru Çitak1
1Department of Biology, Faculty of Science, Gazi University, Ankara, Turkiye.
Turkish journal of biology = Turk biyoloji dergisi
|January 7, 2026
概括
赋予抗微生物耐药性的排泄基因在来自食物的葡萄球菌中很常见. 储降低了阻力,证实了排泄的排泄.
科学领域:
- 微生物学 微生物学
- 分子生物学分子生物学
- 食品安全 食品安全
背景情况:
- 食物传播细菌的抗菌素耐药性是一个越来越令人担忧的问题.
- 排泄在细菌对抗生素和杀菌剂的耐药性方面发挥着重要作用.
- 监测食物链中的耐药基因对公共健康至关重要.
研究的目的:
- 为了研究表型耐药性和排泄基因在Staphylococcus spp. 来自乳制品和肉类.
- 评估排水在抗生素和生物制剂耐药性的作用.
- 为了确定特定的排泄基因的流行率.
主要方法:
- 隔离和识别的葡萄球菌 spp. 来自132个乳制品和肉类样本.
- 使用微稀释方法进行抗微生物敏感性测试.
- 通过储抑制和基因检测通过实时PCR评估的排泄活性.
主要成果:
- 26%的分离物体对至少一种抗生素,主要是四环素和 cefuroxime,表现出耐药性.
- 对于几种抗生素和生物制剂,reserpine降低了最小抑制度 (MIC),这表明排泄参与.
- 检测到流出基因smr,efrA,efrB,mdeA和norE的高流行率.
结论:
- 排泄基因在食品中的葡萄球菌中广泛存在.
- 现型耐药性通过排泄活动得到证实.
- 控制食物链中耐药基因传播的策略是必要的.
相关概念视频
Development of Antibiotic Resistance
1.3K
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
1.3K
Antimicrobial Proteins
12.9K
Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
12.9K
Antibiotic Selection
59.3K
Overview
59.3K
Gene Regulation in Microbial Communities: Quorum Sensing
506
Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
506


