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Updated: Jan 13, 2026

Forskolin-induced Swelling in Intestinal Organoids: An In Vitro Assay for Assessing Drug Response in Cystic Fibrosis Patients
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在囊性纤维化中高效调节器疗法:解决中东地区不寻常的变体

Said Isse1, Ali Saeed Wahla1, Mateen Haider Uzbeck1

  • 1Respiratory Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE, clevelandclinicabudhabi.ae.

Pulmonary medicine
|January 7, 2026
PubMed
概括

在中东的囊性纤维化 (CF) 患者中,elexacaftor/tezacaftor/ivacaftor (ETI) 治疗显著改善了肺功能,并减少了罕见CFTR变异的恶化. 这项研究支持为这些代表性不足的人群提供更广泛的ETI访问.

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