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Updated: Jan 13, 2026

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
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大肠直肠瘤中的Bacteroides fragilis毒素激活STAT3并驱动微卫星的不稳定性

Muhammad Shahid Mehmood1, Naseeb Danaf2

  • 1Institute of Microbiology, University of Agriculture Faisalabad, Faisalabad, Pakistan.

Annals of medicine and surgery (2012)
|January 7, 2026
PubMed
概括

肠毒性细菌菌 (ETBF) 和其毒素 (BFT) 通过激活STAT3信号来促进结直肠癌 (CRC),导致基因组不稳定. 针对这种微生物致癌轴,为CRC提供了新的治疗策略.

关键词:
这是一种BFT毒素.这种细菌是 Bacteroides fragilis.在STAT3激活过程中,结肠直肠癌是什么意思炎症驱动的致癌发生是炎症驱动的致癌.微卫星的不稳定性瘤微生物组是什么?

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