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Updated: Jan 13, 2026

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods
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Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods

Published on: July 17, 2019

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以人工智能驱动的BRAF抑制剂的新型设计,具有增强的结合亲和力和优化的药物相似性

Zuokun Lu1,2, Aili Zhang1

  • 1Food and Pharmacy College, Xuchang University, Xuchang, Henan, China.

PeerJ
|January 7, 2026
PubMed
概括

人工智能 (AI) 产生了新的BRAF V600E抑制剂,改善了药物相似性和功效,为开发更安全的癌症疗法提供了可扩展的方法. 这种人工智能驱动的方法加速了针对癌症治疗的药物发现.

关键词:
BRAF 抑制剂的使用药物发现 药物发现机器学习是机器学习.分子对接是分子对接.分子动力学模拟模型在瘤学瘤学.

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