患有真菌菌菌病的患者睡眠障碍的患病率和严重程度:一项病例对照研究
Ahmad Vafaeian1, Aidin Shahilooy1, Maryam Daneshpazhooh1
1Autoimmune Bullous Diseases Research Center, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran, tums.ac.ir.
Journal of skin cancer
|January 7, 2026
概括
与健康个体相比,患有菌根性菌病 (MF) 的患者的睡眠质量差显著更高. 评估MF患者的睡眠障碍对于改善其整体生活质量至关重要.
科学领域:
- 皮肤病学 皮肤病学
- 睡眠医学 睡眠医学
- 在瘤学瘤学.
背景情况:
- 菌根性菌症 (MF) 是最常见的皮肤T细胞淋巴瘤类型.
- 关于MF对睡眠和生活质量的影响的证据是有限的,因为它很罕见.
研究的目的:
- 评估患有真菌菌菌病的患者睡眠障碍的患病率和严重程度.
- 为了比较MF患者的睡眠质量与匹配的健康人群.
主要方法:
- 一项涉及72名多发性纤维患者和72名健康对照者的病例控制研究.
- 使用匹兹堡睡眠质量指数 (PSQI) 和失眠严重程度指数 (ISI) 评估睡眠质量.
- 睡眠质量差的定义是PSQI得分>5.
主要成果:
- 与对照组相比,MF患者报告的PSQI (10.22) 和ISI (16.28) 中位数得分明显高 (PSQI:5.12,ISI:6.39).
- 后勤回归证实了MF和睡眠质量差之间存在显著的关联 (PSQI和ISI的p < 0.0001).
- 年龄,性别,和疾病阶段等因素与睡眠质量不佳无关.
结论:
- 睡眠障碍在mycosis fungoides患者中明显更为普遍和严重.
- 评估MF患者的睡眠质量对于提高他们的生活质量至关重要.
- 早期发现和治疗睡眠障碍可以改善患者的治疗结果.
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