中东地区的性食道炎:综合系统性审查的洞察力
Nouran Alwisi1, Sidra Abdul Moqeeth1, Muneera Al-Mohannadi1,2
1College of Medicine, QU Health Qatar University Doha Qatar.
概括
中东地区的性食道炎 (EoE) 显示出全球症状和治疗模式. 然而,独特的区域因素和诊断挑战需要提高对这种慢性食道疾病的认识和标准化方案.
科学领域:
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
- 流行病学 流行病学
背景情况:
- 生性食道炎 (EoE) 是一种慢性免疫媒介食道疾病,全球发病率正在上升.
- 关于中东地区的EoE数据有限且分散.
- 本综述综合了中东人口中EoE的证据.
研究的目的:
- 在中东全面审查EoE的临床表现.
- 分析过敏并发症,诊断实践和管理策略.
- 确定EoE护理中的区域特点和挑战.
主要方法:
- 在主要数据库 (PubMed,Scopus,Embase,Web of Science) 进行系统搜索,直到2025年7月.
- 包括报告中东国家EoE患者原始数据的研究.
- 使用Joanna Briggs Institute (JBI) 工具进行数据提取和质量评估.
主要成果:
- 分析了67项研究,其中包括来自11个中东国家的2870名EoE患者.
- 观察到男性占主导地位 (2:1成人,2.5:1儿童);消化不良和食物受损是关键症状.
- 过敏并发症常见;诊断标准一致,但诊断不足;粘膜重塑和狭窄表明延迟;PPI,皮质类固醇和饮食变化是主要治疗方法.
结论:
- 中东的EoE患者共享全球临床和管理模式.
- 区域因素,如饮食和过敏,以及诊断挑战,需要注意.
- 提高临床医生的意识和标准化的诊断协议对于最佳的EoE护理至关重要.
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