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Updated: Jan 13, 2026

In vivo Application of the REMOTE-control System for the Manipulation of Endogenous Gene Expression
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Published on: March 29, 2019

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可通过适应剂调节的体内基因表达

Jack Bryant1, Laura Herron1, Yesh Doctor1

  • 1Department of Bioengineering, University of California San Diego, CA, USA.

bioRxiv : the preprint server for biology
|January 7, 2026
PubMed
概括

研究人员开发了一种小型的RNA开关,称为适应体 (ADAR可调节的aptamer),用于精确控制基因表达. 该系统通过利用小分子和内源RNA编辑来实现可调节的基因疗法,显示出逆转小鼠肥胖的前景.

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