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慢性病患者的疼痛经历和国际差异及其管理
Rupesh Raina1,2, Nikhil Nair3, Rohan Kumar4
1Department of Nephrology, Akron Children's Hospital, Akron, OH USA.
Clinical kidney journal
|January 7, 2026
概括
非透析慢性病 (ND-CKD) 患者的疼痛管理在全球范围内有所不同. 止痛药处方的国际差异,特别是阿片类药物和NSAIDs,影响患者的疼痛和生活质量.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 疼痛管理 疼痛管理
- 与健康相关的生活质量 (HRQOL)
背景情况:
- 在非透析慢性病 (ND-CKD) 患者中,慢性疼痛显著降低HRQOL.
- 在ND-CKD患者的疼痛管理带来了独特的挑战.
- 止痛药处方实践的国际差异可能会影响疼痛体验和HRQOL.
研究的目的:
- 调查止痛药处方模式的国际差异.
- 为了检查止痛药使用,疼痛强度和HRQOL在3-5期ND-CKD患者之间的关系.
主要方法:
- 一个使用CKDopps (2013-2020) 数据的跨国观察队列研究.
- 包括来自巴西,法国和美国科实践的成年患者.
- 在HRQOL评估 (KDQOL-SF) 后6个月内处方的止痛药 (NSAID,阿片类药物,其他).
主要成果:
- 止痛药在美国最常被处方,与巴西和法国相比,阿片类药物的使用率更高.
- 与法国和美国不同的是,在巴西,NSAID的使用很常见,甚至在晚期CKD中也是如此.
- 疼痛强度增加与所有测量子域的HRQOL较差相关.
结论:
- 在ND-CKD患者的疼痛报告和止痛药处方方面存在显著的国际差异.
- 需要进一步的研究,包括随机对照试验,以优化止痛药的有效性和安全性.
- 改善疼痛管理对于提高ND-CKD患者报告结果至关重要.
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