关于在动脉瘤下大脑关节出血后结果选择的国际立场文件
Christopher R Andersen1,2,3, Gordon Fernie4, Justin Presseau5,6
1Malcolm Fisher Department of Intensive Care Medicine, Royal North Shore Hospital, Sydney, Australia (C.R.A.).
Stroke
|January 7, 2026
概括
研究人员就动脉瘤下arachnoid出血 (aSAH) 研究的关键健康领域达成共识. 这旨在在aSAH研究中标准化结果测量和改进以患者为中心的护理.
科学领域:
- 神经科学是一个神经科学.
- 临床研究 临床研究
- 患者的治疗结果.
背景情况:
- 动脉瘤下关节出血 (aSAH) 研究缺乏一致和与患者相关的健康结果报告.
- 目前的结果指标没有充分反映受aSAH影响的个体的优先事项.
研究的目的:
- 建立关于aSAH研究的基本健康领域的国际共识.
- 为临床医生和研究人员在选择aSAH研究的适当结果措施时提供指导.
主要方法:
- 利用了来自25多个国家的239名参与者参与的国际优先级调查.
- 员工混合面对面/在线共识会议与69个不同的利益相关者,包括患者和专家.
- 通过多学科工作组,为每个健康领域建立共识定义.
主要成果:
- 在6个核心健康领域达成共识 (>70%的认可),用于aSAH研究.
- 定义的领域包括:与健康相关的生活质量,生存,认知和执行功能,功能结果,延迟的脑缺血/心脏病发作和再出血/动脉瘤消灭.
结论:
- 本国际立场声明提供了一个核心领域,用于在aSAH研究中标准化结果选择.
- 已建立的领域将有助于塑造未来的研究议程,以评估新的aSAH治疗方法.
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