使用行政数据的研究中回顾期的长度:一个范围审查
Miriam Chisholm1, Sricharan Navuluri1, Moronke Ogundolie2
1Duke University School of Medicine.
Epidemiologic reviews
|January 7, 2026
概括
在电子健康记录 (EHR) 和索赔数据中确定正确的回顾期对于现实世界的证据至关重要. 这次审查发现回顾期因临床结果而异,突出显示了流行病学研究中需要量身定制的方法.
科学领域:
- 流行病学研究 流行病学研究
- 现实世界的证据生成
- 健康 数据科学 数据科学
背景情况:
- 行政数据,包括电子健康记录 (EHR) 和索赔数据,对于流行病学中的真实世界证据 (RWE) 至关重要.
- 观察性研究需要定义回顾期以捕捉基线特征,与临床试验不同.
- 基于特定的临床结果,目前还没有针对最佳回顾期的指导方针.
研究的目的:
- 对流行病学研究中的回顾期进行方法学研究的范围审查.
- 评估使用行政数据的研究中使用的回顾期的频率和变化.
- 为研究人员提供有关选择适当的回顾期的研究信息.
主要方法:
- 在PubMed中搜索了使用电子健康记录 (EHR),索赔数据或具有定义回顾期的国际注册表的研究.
- 包括方法研究,重点关注回顾期的应用.
- 分析了262项针对不同临床结果的研究.
主要成果:
- 流行病学研究中的回顾期有很大的不同,从12小时到39年不等.
- 回顾期的长度取决于所研究的特定临床结果.
- 通常研究的领域包括药理学,心血管疾病,癌症和医疗保健利用.
结论:
- 对于使用行政数据的流行病学研究来说,对回顾期的全方位方法是不够的.
- 针对临床背景的量身定制的回顾期是产生可靠的真实世界的证据所必需的.
- 未来的研究应该调查回顾期对研究不足的临床结果的影响.
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