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相关概念视频

Functional Classification of Joints01:09

Functional Classification of Joints

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Functional Classification of Joints
The functional classification of joints is determined by the amount of mobility between the adjacent bones. Joints are functionally classified as a synarthrosis or immobile joint, an amphiarthrosis or slightly moveable joint, or as a diarthrosis, a freely moveable joint. Fibrous and cartilaginous joints can be functionally classified as either synarthroses  or amphiarthroses, whereas all synovial joints are classified as diarthroses.
Synarthrosis
An...
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相关实验视频

Updated: Jan 13, 2026

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
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解码关节疾病:识别关节盘中的特定阶段和功能模式

Pascal Eber1,2, Ana M P Baggio1,3, Yannick M Sillmann1,4

  • 1Division of Oral and Maxillofacial Surgery, Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard School of Dental Medicine, Boston, MA, USA.

Stem cell reviews and reports
|January 7, 2026
PubMed
概括
此摘要是机器生成的。

在关节 (TMJ) 关节盘中识别生物标志物有助于了解关节疾病 (TMD). 这些生物标志物的分类有助于早期检测和个性化治疗策略TMD.

关键词:
人工智能,偏见,偏见生物标志物生物标志物疾病进展 疾病进展部关节的圆盘 部关节的圆盘短关节疾病 短关节疾病

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A Morphometric and Cellular Analysis Method for the Murine Mandibular Condyle
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相关实验视频

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Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
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Optical Sectioning and Visualization of the Intervertebral Disc from Embryonic Development to Degeneration
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A Morphometric and Cellular Analysis Method for the Murine Mandibular Condyle
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A Morphometric and Cellular Analysis Method for the Murine Mandibular Condyle

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科学领域:

  • 生物标志物 生物标志物
  • 免疫组织化学 免疫组织化学
  • 关节疾病 (TMD) 是一种关节疾病.

背景情况:

  • 部部疾病 (TMD) 影响约30%的人口,病因不明.
  • 盘位移和退化与生物机械功能障碍有关.
  • 关节盘生物标志物是了解TMD机制和改善诊断/治疗的关键.

研究的目的:

  • 审查TMJ关节盘中的免疫组织化学生物标志物.
  • 专注于内部乱和圆盘位移.
  • 将生物标志物与临床,放射学和组织学发现联系起来,以获得功能和特定阶段的相关性.

主要方法:

  • 对数据库和期刊进行系统的文献搜索.
  • 包括使用免疫组织化学和对照组的研究.
  • 根据PRISMA指南分析了生物标志物模式,临床,放射学,组织学发现和人口统计数据.

主要成果:

  • 包括511名患者 (579个样本) 和132个对照 (158个样本).
  • 确定了24种参与炎症,ECM重塑和退化的生物标志物.
  • 按功能和阶段分类的生物标志物,用于早期检测,分期和个性化治疗.

结论:

  • 磁盘活检提供了有关TMD从位移到退化进展的见解.
  • 磁盘活检的临床实用性受到侵入性,伦理和缺乏标准化的协议的限制.
  • 需要进一步的研究来验证生物标志物概况和可靠的研究设计.