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Updated: Jan 13, 2026

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使用生理学基础的药理动力学建模和模拟来预测肝硬化患者的抗高血压药物剂量

Mai Tarek1, Ahmed A Ali1, Reda Biomy2

  • 1Clinical Pharmacy Department, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.

Journal of clinical pharmacology
|January 7, 2026
PubMed
概括

基于生理学的药理动力学 (PBPK) 模型准确地预测肝硬化患者所需的抗高血压药物剂量调整. 这些模型指导肝病各个阶段的安全有效的药物管理.

关键词:
PBPKK PBPK 的意思是什么意思抗高血压药物的使用.心血管疾病心血管疾病肝硬化是肝硬化的一种疾病.肝功能受损 肝功能受损药物动力学建模和仿真

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