在产卵母的高峰,中期和下降卵生产阶段,肠道微生物组,代谢途径和肠道基因表达的变化
Md Ahosanul Haque Shahid1, Rajesh Jha1, Birendra Mishra1
1Department of Human Nutrition, Food and Animal Sciences, University of Hawaii at Manoa, Honolulu, HI, USA.
Poultry science
|January 7, 2026
概括
老年由于肠道微生物群的变化,营养吸收减少和免疫力受损而导致卵产量减少. 了解这些变化可以改善羊群的健康和生产力.
科学领域:
- 动物科学动物科学
- 微生物学 微生物学
- 基因组学就是基因组学.
背景情况:
- 随着母年龄的增长,蛋产量下降,影响了家禽业.
- 肠道健康,营养的可用性和生理状态对于持续的卵子生产至关重要.
研究的目的:
- 为了研究产母中与年龄相关的 cecal 微生物群变化,预测的代谢途径和 ileal 基因表达.
- 为了澄清肠道健康和生理学对老年蛋产量下降的影响.
主要方法:
- 16S rRNA基因测序来自在卵产量高峰期,中衰期和衰期阶段的卵.
- 定量PCR (qPCR) 用于叶基因表达分析.
- 生物信息分析包括PICRUSt2用于功能预测和STAMP用于统计分析.
主要成果:
- 微生物多样性随着年龄的增长而下降,细菌分类和预测代谢功能的明显变化.
- 抗氧化剂,紧密结合和营养物质转运基因的细胞表达在老母中下降.
- 免疫标志物表明,在衰退阶段的母中,免疫反应受到损害,同时有细胞损伤和泄漏的证据.
结论:
- 肠道微生物群,营养物质运输和免疫功能与年龄相关的变化有助于产卵母的卵产量减少.
- 研究结果为开发策略提供了洞察力,以提高老年的群体健康和生产力.
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