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Updated: Aug 14, 2026

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来自阿斯伯吉路斯尼格尔的蛋白酶PepA的propeptide工程用于增强催化活性

Anrong Zhang1, Chenghe Chang1, Bingbing Fan1

  • 1State Key Laboratory of Animal Nutrition, Department of Animal Nutrition and Feed Science, China Agricultural University, Beijing, 100193, China.

International journal of biological macromolecules
|January 7, 2026
PubMed
概括

工程阿斯巴达蛋白酶PepA是酶成熟的关键. 突变显著提高了PepA活动,为蛋白酶工程提供了洞察力.

关键词:
阿斯巴拉提克蛋白质酶是什么催化活动是催化活动.酸工程 酸工程 酸工程局部导向的突变发生.

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Bacterial Protein Maturation01:26

Bacterial Protein Maturation

Bacterial protein maturation is a tightly regulated process that ensures newly synthesized polypeptides achieve correct functional conformations. This maturation involves a series of modifications, folding events, and quality control steps, often assisted by specialized chaperone proteins.N-Terminal ModificationsThe maturation of bacterial polypeptides begins cotranslationally as the polypeptide exits the ribosome. The first amino acid, N-formylmethionine (fMet), is typically modified at the...