肠道菌群中的多糖和肠道平衡中的Codonopsis pilosula多糖:一篇综述
Xiao-Juan Wang1, Xiang-Yang Li1, Jin Shang1
1The First School of Clinical Medicine, Lanzhou University, Lanzhou 730000, China; Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, China; Key Laboratory of Biotherapy and Regenerative Medicine of Gansu Province, The First Hospital of Lanzhou University, Lanzhou 730000, China.
科多诺普西斯 (Codonopsis pilosula) 多糖 (CPPs) 调节肠道微生物群和代谢物,支持肠道健康. 本综述探讨了CPP的使用情况.
科学领域:
- 药理学 药理学是指药理学的学科.
- 微生物学 微生物学
- 胃肠病学 胃肠病学
背景情况:
- 肠道菌群失调与肠道透性增加,屏障功能障碍和全身炎症有关,有助于各种疾病.
- 科多诺opsis pilosula 多糖 (CPP) 是中国传统医学的关键生物活性化合物,在维持肠道平衡方面发挥着显著作用.
- 肠道微生物群的破坏与许多健康状况有关,突出显示了对有效调节剂的需求.
研究的目的:
- 系统地审查CPPs对肠道菌群及其代谢物的影响.
- 阐明CPP维持肠道平衡的机制.
- 评估CPPs作为预防和治疗肠道疾病的益生菌的潜力.
主要方法:
- 对研究CPP及其对肠道微生物群的影响的文献综述.
- 对CPPs对短链脂肪酸,二次胆汁酸和托代谢物的影响的研究分析.
- 综合了关于CPPs在调节肠道菌群组成和功能中的作用的发现.
主要成果:
- CPPs调节肠道菌群,影响有益代谢物的产生.
- 有证据表明,CPP可以增强肠道屏障功能,减少炎症反应.
- CPP增加了短链脂肪酸,二次胆汁酸和托代谢物的水平.
结论:
- CPPs在调节肠道菌群和代谢物方面表现出显著的潜力.
- CPP在维持肠道平衡和屏障完整性方面发挥着至关重要的作用.
- CPP可以作为治疗肠道疾病的新型益生菌.
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