在重症脑静脉血栓形成后的减压手术后的生活质量
Mayte Sanchez van Kammen1, Sanjit Aaron2, Jorge M Ferreira3
1Department of Neurology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
概括
脑静脉血栓瘤 (CVT) 的减压手术显著影响生活质量,大多数幸存者在手术后一年报告日常活动,疼痛和心理健康问题.
科学领域:
- 神经外科 神经外科
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 减压性手术对于严重脑静脉血栓塞 (CVT) 患者来说至关重要,这些患者面临大脑.
- 关于手术后与健康相关的生活质量 (HRQoL) 的数据有限.
研究的目的:
- 评估成人患者的HRQoL在进行CVT的减压手术后.
- 为了确定手术后12个月HRQoL结果的预测因素.
主要方法:
- 在15个中心进行了112名接受压缩减压手术的成年CVT患者的前性队列研究 (DECOMPRESS-2).
- 在6个月和12个月时使用EQ5D-3L和视觉模拟量表 (VAS) 评估HRQoL.
- 统计分析包括完整案例,多重归算,最佳/最差情况,托比特和线性回归.
主要成果:
- 在12个月后,84%的幸存者报告至少一个EQ5D-3L子域存在问题 (通常活动,疼痛,焦虑/抑郁最常见).
- 中位数EQ5D-3L得分为0.70;中位数VAS为70.
- 更高的年龄,居住在中等收入国家,以及手术前昏迷预测HRQoL结果较差.
结论:
- 在接受压缩减缓手术的CVT患者中,超过80%的患者在手术后12个月经历了持续的HRQoL问题.
- 年龄,社会经济因素 (中等收入国家地位) 和手术前的神经状态是长期生活质量的关键决定因素.
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