输血和GnRH主动激素的后置可逆脑病综合征后的输血和GnRH主动激素的后置可逆脑病综合征
Sanjai Subha1, Donal Skelly2, Damian Jenkins2
1Department of Neurology, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK sanjai2888@gmail.com.
Practical neurology
|January 7, 2026
概括
后可逆脑病综合征 (PRES) 可以发生在输血后,特别是当与激素释放激素 (GnRH) 激素治疗结合时. 及时识别和管理是全面临床康复的关键.
科学领域:
- 神经学 神经学
- 血液学 血液学 血液学
- 放射学 放射学是一门学科.
背景情况:
- 后回性脑病综合征 (PRES) 是一种急性神经疾病.
- 常见的PRES触发因素包括高血压,功能障碍和免疫抑制疗法.
- 输血和GnRH激动剂治疗是PRES不常见的原因.
研究的目的:
- 在输血和GnRH激动剂治疗后报告PRES病例.
- 强调考虑输血作为潜在的PRES触发器的重要性.
- 强调需要对接受输血和GnRH激动剂的患者进行仔细监测.
主要方法:
- 一个44岁的妇女患有因流血引起的贫血病的病例报告.
- 在3天内给予5个单位的输血.
- 启动戈塞林治疗,随后呈现出状况.
主要成果:
- 大脑MRI揭示了与PRES相一致的血管性胀和脑下下垂体出血.
- 患者的治疗包括抗发作药物,抗高血压药物和停止使用戈塞林.
- 随访成像显示PRES完全消失和完全临床康复.
结论:
- 应考虑PRES是输血的潜在并发症,特别是在同时使用GnRH激动剂时.
- 逐渐纠正贫血和密切的输血后监测有助于早期识别PRES.
- 这一案例强调了识别不太频繁的PRES触发器的重要性.
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