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Updated: Jan 13, 2026

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AKAP95凝结物调节转录,可以在MLL融合驱动的瘤发生中作为点

Xiang Yan1, Yongkun Luan1, Yi Zhu1

  • 1Department of Biomedical and Engineering, College of Biology, Hunan University, Changsha, Hunan, China.

Nature communications
|January 7, 2026
PubMed
概括

像AKAP95这样的RNA结合蛋白 (RBPs) 通过调节转录凝聚物,对MLL重组的白血病产生至关重要. 用酸针对这些凝聚物抑制了白血病细胞的增殖.

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