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Updated: Jan 13, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Published on: August 4, 2019

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53的状态决定了对脱甲基化剂阿扎西蒂丁和达西的表观遗传反应

Emma Langdale Hands1, Arndt Wallmann1, Gabrielle Oxley1

  • 1MRC Toxicology Unit, University of Cambridge, Tennis Court Road, Cambridge, UK.

EMBO reports
|January 7, 2026
PubMed
概括

5'-阿扎丁 (Aza) 和5-Aza-2'-脱氧丁 (Dac) 是具有独特细胞反应的脱甲基化药物. P53状态可以作为预测对这些表观遗传疗法的反应的新生物标志物.

关键词:
亚扎西蒂丁是一种阿扎西蒂丁.德西塔类药物 德西塔类药物表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.在R-Loops中使用R-Loops.在 p53 里,p53 是一个 p53 的类型.

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