精液质量与精液中基本和非基本元素的关联
Adnan M Massadeh1, Osamah Batiha2, Waad E Abu Diak3
1Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, 22110, Jordan. massadeh@just.edu.jo.
Biological trace element research
|January 7, 2026
概括
精液血中的重金属会对男性生育能力产生负面影响. 较高的和水平与约旦男性的精子运动性降低和形态异常有关.
科学领域:
- 环境毒理学环境毒理学
- 生殖生物学 生殖生物学
- 分析化学 分析化学
背景情况:
- 长时间接触重金属可能会损害人类精液质量,并导致男性不孕.
- 了解精液等离子体中的元素概况对于评估男性生殖健康至关重要.
研究的目的:
- 为了确定人类精液等离子体中17种元素的流行程度.
- 在约旦人口中调查元素度和精液质量参数 (运动性,数量,形态) 之间的关联.
主要方法:
- 诱导合血质谱法 (ICP-MS) 用于分析97个精液血样本.
- 评估了精液质量参数,包括精子运动性,数量和形态.
- 方法验证证实了良好的线性 (R2>0.997) 和精度 (%RSD <5%).
主要成果:
- (Ca) 和 (Cr) 是最丰富的元素. 在基本元素和精子形态或数量之间没有发现显著的关联.
- 高 (In) 和 (Cd) 度与精子运动性降低和形态异常有很强的相关性.
- 精子运动率低与更高的 (V) 和 (As) 水平有关.
- 正常的精液参数显示高 (Ga) 水平,而运动性降低与 (Mn),Cr和Ca的增加有关.
结论:
- 像In和Cd这样的特定元素具有生殖毒性,对精子运动和形态产生负面影响.
- 精液等离子体的元素分析为男性不孕症因素提供了新的见解.
- 这项研究为精液中以前未报告的元素提供了新的数据.
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