Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

1.2K
Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
1.2K
Local Anesthetics: Differential Sensitivity of Nerve Fibers01:24

Local Anesthetics: Differential Sensitivity of Nerve Fibers

1.4K
Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
1.4K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Botulinum neurotoxin for lip flip.

JPRAS open·2026
Same author

Intradermal Injections of 10% Glucose (Sihler G) for Scalp Hair Regrowth: A Randomized, Evaluator-Blinded Pilot Study.

Aesthetic plastic surgery·2026
Same author

Gas subcision with PDLLA (Juvelook): Evaluating a hybrid mechanical-biologic approach for atrophic acne scars.

JPRAS open·2026
Same author

Shoulder contouring with botulinum toxin and fillers.

JPRAS open·2026
Same author

Temporoparietalis Muscle: A Cadaveric Study of 60 Hemisides.

Plastic and reconstructive surgery. Global open·2026
Same author

Synergistic lower blepharoplasty and midface lift: The role of multi-directional thread fixation.

JPRAS open·2026

相关实验视频

Updated: Jan 13, 2026

Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors
04:59

Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors

Published on: September 27, 2019

13.0K

使用PDLLA进行皮内与皮下皮肤增强剂注射的比较疼痛评估:一种随机的双盲分注射研究.

Kyuho Yi1, Isabella Rosellini2, Kian Hong Lau3

  • 1Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, Korea. kyuho90@daum.net.

Aesthetic plastic surgery
|January 7, 2026
PubMed
概括

皮下注射的Poly-D,L-乳酸 (PDLLA) 注射要比皮肤内注射的疼痛要少得多. 这一发现表明,皮下给药可能会提高患者的舒适性和服从性.

关键词:
化品的技术 化品的技术注射,皮肤内注射,皮肤内注射在注射,皮下注射.疼痛测量方法 疼痛测量方法聚乳酸是一种多乳酸.

更多相关视频

Determining heat and mechanical pain threshold in inflamed skin of human subjects
13:21

Determining heat and mechanical pain threshold in inflamed skin of human subjects

Published on: January 14, 2009

21.3K
Intralymphatic Immunotherapy and Vaccination in Mice
07:33

Intralymphatic Immunotherapy and Vaccination in Mice

Published on: February 2, 2014

23.9K

相关实验视频

Last Updated: Jan 13, 2026

Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors
04:59

Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors

Published on: September 27, 2019

13.0K
Determining heat and mechanical pain threshold in inflamed skin of human subjects
13:21

Determining heat and mechanical pain threshold in inflamed skin of human subjects

Published on: January 14, 2009

21.3K
Intralymphatic Immunotherapy and Vaccination in Mice
07:33

Intralymphatic Immunotherapy and Vaccination in Mice

Published on: February 2, 2014

23.9K

科学领域:

  • 皮肤病学 皮肤病学
  • 审美医学是一种美学医学.
  • 生物材料科学 生物材料科学

背景情况:

  • 聚-D,L-乳酸 (PDLLA) 皮肤增强剂用于生物刺激性皮肤再生.
  • 对于PDLLA的不同注射技术之间的疼痛感知存在有限的比较数据.

研究的目的:

  • 为了比较患者报告的皮肤内和皮肤下PDLLA注射之间的疼痛.
  • 利用随机,双盲,分注设计进行了强大的比较.

主要方法:

  • 21名参与者使用32G针进行了10次面部注射 (5次皮内注射,5次皮下注射).
  • 在注射后立即使用视觉模拟量表 (VAS) 量化疼痛.
  • 主要结果:平均VAS分数的差异;次要:年龄和性别影响.

主要成果:

  • 与皮下注射 (3.85) 相比,皮内注射的VAS平均得分 (6.18) 显著更高.
  • 没有观察到任何基于性别的疼痛差异.
  • 年轻的患者 (<40) 报告说,皮内注射增加了疼痛,但年龄没有影响皮下疼痛.

结论:

  • 皮下PDLLA注射比皮内注射要少得多.
  • 较低的神经密度和皮肤阻力可能有助于减少皮下给药时的疼痛.
  • 皮下注射是一种潜在的优选方法,可以提高患者的舒适性和服从性.