毒理学研究人员联盟2024年年度报告
Kim Aldy1,2, Shao Li1, Mari Costantini1
1American College of Medical Toxicology, 10645 N Tatum Blvd., Suite 200-111, Phoenix, AZ, 85028, USA.
概括
毒理学调查者联盟 (ToxIC) 核心注册表在2024年跟踪了8,868名患者,其中乙醇,阿片类药物和止痛药是最常见的暴露. 这个医学毒理学数据库现在拥有超过111,000个病例.
科学领域:
- 医学毒理学医学毒理学
- 临床研究 临床研究
- 公共卫生监督 公共卫生监督
背景情况:
- 美国医学毒理学学院 (ACMT) 在2010年建立了毒理学研究人员联盟 (ToxIC) 核心注册表.
- 该注册表系统地收集有关医学毒理学咨询的数据.
- 这些数据有助于理解暴露模式和结果.
研究的目的:
- 提交第十五次年度报告的毒性IC核心注册表.
- 从2024年开始总结患者数据,暴露剂和结果.
- 分析2010-2024年间阿片类药物和精神活性药物暴露的趋势.
主要方法:
- 从医院和临床医疗毒理咨询收集数据.
- 包括未被识别的患者人口统计,暴露剂,临床迹象,症状,治疗和死亡率.
- 分析了从2024年开始的8868例新病例和从2010年到2024年累计数据.
主要成果:
- 2024年的数据包括来自美国23个州和3个国际国家的41个地点的8868名患者.
- 乙醇 (17.8%),阿片类药物 (15.8%),非阿片类止痛药 (10.5%) 和同情药物 (7.6%) 是最常见的暴露剂.
- 报告共有107起死亡事故,死亡率为1.2%.
结论:
- 毒性物质核心注册表继续成为医学毒理学数据的宝贵资源.
- 乙醇和阿片类药物仍然是严重的公共卫生问题.
- 纵向分析揭示了物质暴露的趋势,为公共卫生战略提供了信息.
相关概念视频
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In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
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