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Updated: Jan 13, 2026

A Real-time Potency Assay for Chimeric Antigen Receptor T Cells Targeting Solid and Hematological Cancer Cells
08:46

A Real-time Potency Assay for Chimeric Antigen Receptor T Cells Targeting Solid and Hematological Cancer Cells

Published on: November 12, 2019

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通过增强的TRAF介导的TNF信号传递,HVEM辅助刺激域增强了CAR T细胞对固体瘤的疗效

Shishuo Sun1,2,3, Wanxin Zhao1, Yibing Liang1

  • 1Cancer Institute, Cellular Therapeutics School of Medicine, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, P.R. China.

Cell communication and signaling : CCS
|January 8, 2026
PubMed
概括

疹病毒进入介导体 (HVEM) 协同刺激域通过促进TNF信号传递和T细胞代谢,显著增强仿真抗原受体 (CAR) T细胞对固体瘤的疗效. 这项研究表明,HVEM的优势超过4-1BB,改善了CAR T细胞治疗.

关键词:
卡特 卡特 卡特造价刺激分子的分子.在这里,HVEMEM HVEMEM固体瘤是一个固体瘤.交通运输 交通运输是什么

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