在乳腺癌新辅助化疗期间维持生活质量的家庭以患者为中心的体育活动计划:AURORA随机对照试验协议
Denise Montt-Blanchard1,2, Karol Ramírez-Parada3, Viviana Montecinos4
1School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile. denisemontt@uc.cl.
Trials
|January 8, 2026
概括
这项研究调查了Aurora干预措施,以改善乳腺癌 (BC) 接受化疗的女性的体力活动坚持. 该计划旨在提高生活质量和身体功能,在治疗期间提供以患者为中心的运动方法.
科学领域:
- 在瘤学瘤学.
- 运动科学 运动科学
- 行为科学 行为科学
背景情况:
- 身体活动对乳腺癌 (BC) 患者有好处,但在新辅助化疗期间的坚持率很低.
- 欧罗拉干预针对BC患者的多维需求和身体活动障碍.
- 这项研究评估了Aurora干预与接受化疗的BC患者的标准护理.
研究的目的:
- 评估奥罗拉干预对BC患者生活质量的影响.
- 评估干预对功能能力和生物标志物的影响.
- 为了确定奥罗拉计划是否与标准护理相比改善了身体活动的坚持,强度和持续时间.
主要方法:
- 一项为期9周的随机对照试验,涉及30名女性BC患者 (70岁以下) 在智利接受新辅助化疗.
- 参与者接受了标准的在线教育,然后随机分配到奥罗拉干预套件或控制套件中.
- 混合方法方法包括问卷,患者日记,采访,功能能力测试和生物标记分析.
主要成果:
- 据假设,奥罗拉干预会对主要结果 (生活质量) 和次要结果 (功能能力,生物标志物) 产生积极影响.
- 预计这项干预措施将改善身体活动的坚持,强度和持续时间.
- 该研究预计,与标准护理相比,Aurora计划的积极影响显著.
结论:
- 预计使用以患者为中心的设计和COM-B模型的Aurora干预措施将有效地解决BC患者的需求和障碍.
- 该计划旨在增强身体活动的坚持和改善乳腺癌患者的健康结果.
- 这种干预提供了一个有希望的方法来支持化学疗法期间患有乳腺癌的妇女.
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