一个患有希恩综合征的妇女的细胞巨乳病毒结肠炎
Chen-Yu Wang1,2, Te-Chun Shen2,3,4, Te-Hung Chen5
1Department of Education, China Medical University Hospital, Taichung, Taiwan.
QJM : monthly journal of the Association of Physicians
|January 8, 2026
概括
细胞巨乳病毒 (CMV) 大肠炎可以影响有微妙免疫问题的老年人. 希恩综合征和葡萄糖皮质激素的使用可能会增加风险,在患有持续性胃肠道症状的患者中需要考虑.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 内分泌学 在内分泌学.
背景情况:
- 细胞巨乳病毒 (CMV) 大肠炎通常影响免疫力低下的个体.
- 它越来越多地观察到老年人和那些微妙的免疫功能障碍的人.
- 希恩综合征,导致hypopituitarism和需要葡萄糖皮质类药物替代,呈现出一个独特的免疫脆弱性.
研究的目的:
- 报告一种罕见的CMV大肠炎病例,发生在一个患有希恩综合征的患者身上.
- 突出希恩综合征,葡萄糖皮质类药物治疗和老年人中CMV大肠炎之间的潜在联系.
- 强调需要考虑CMV大肠炎的老年患者胃肠道症状和内分泌功能障碍.
主要方法:
- 一个70岁的妇女的病例报告,右下象限疼痛和腹.
- 诊断工作包括内镜检查,本体病理学与免疫组织化学证实CMV大肠炎.
- 患者有史以来的Sheehan综合征,并且正在接受长期的皮质醇替代疗法.
主要成果:
- 内镜检查显示,胃肠道中存在广泛的性病变.
- 组织病理学证实了CMV大肠炎.
- 用甘西克洛维尔和瓦尔甘西克洛维尔治疗导致了完全的临床解决.
结论:
- 在没有明显的免疫抑制的情况下,CMV大肠炎可能发生在老年患者中.
- 希恩综合征和慢性葡萄糖皮质激素使用可能会使个人易患CMV大肠炎.
- 临床医生应考虑CMV大肠炎的老年患者呈现持续的胃肠道症状和内分泌疾病或使用皮质类固醇.
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