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Updated: Jan 13, 2026

Matrix-assisted Laser Desorption/Ionization Time of Flight MALDI-TOF Mass Spectrometric Analysis of Intact Proteins Larger than 100 kDa
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Matrix-assisted Laser Desorption/Ionization Time of Flight MALDI-TOF Mass Spectrometric Analysis of Intact Proteins Larger than 100 kDa

Published on: September 9, 2013

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通过在电泳时间尺度中整合电子,碰撞和基于光子的碎片化技术,在10-70kDa的质量范围内覆盖完整的蛋白质的广泛的脊柱裂隙覆盖

Qianjie Wang1,2, Qianyi Wang1, Rafael D Melani3

  • 1Department of Chemistry, Michigan State University, East Lansing, Michigan 48824, United States.

Journal of the American Society for Mass Spectrometry
|January 8, 2026
PubMed
概括

毛细管区电泳 (CZE) - 双重质谱 (MS/MS) 通过整合多种碎片化方法来增强蛋白形状分析. 这种方法显著提高了全面的自上而下的蛋白质组学 (TDP) 的骨干裂解覆盖率.

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