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Updated: Jan 13, 2026

Molecular Profiling of the Invasive Tumor Microenvironment in a 3-Dimensional Model of Colorectal Cancer Cells and Ex vivo Fibroblasts
10:33

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Published on: April 29, 2014

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与EMT相关的STC2+恶性细胞状态,瘤微环境重塑,以及结肠直肠癌中单细胞和空间转录学揭示的较差预后

Kai Gui1, Tianyi Yang1, Chengying Xiong1

  • 1School of Laboratory Medicine, Chongqing Medical University, Key Laboratory of Clinical Laboratory Diagnostics, Ministry of Education, Chongqing, 400016, China.

Oncology research
|January 8, 2026
PubMed
概括

研究人员确定了一种特定的结肠直肠癌 (CRC) 细胞子集,由STC2表达标记,通过瘤微环境 (TME) 内的独特代谢和信号通路驱动不良预后. 这一发现突出了CRC的潜在治疗目标.

关键词:
大肠直肠癌 (CRC) 是一种癌症.果糖的新陈代谢过程机器学习是机器学习.预后 预后 预后瘤微环境 (TME) 是指瘤的微环境.

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