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Updated: Jan 13, 2026

Enhancement of Apoptotic and Autophagic Induction by a Novel Synthetic C-1 Analogue of 7-deoxypancratistatin in Human Breast Adenocarcinoma and Neuroblastoma Cells with Tamoxifen
19:44

Enhancement of Apoptotic and Autophagic Induction by a Novel Synthetic C-1 Analogue of 7-deoxypancratistatin in Human Breast Adenocarcinoma and Neuroblastoma Cells with Tamoxifen

Published on: May 30, 2012

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在肝细胞癌中通过ROS介导的JNK/p38 MAPK通路激活促进细胞亡和线粒体功能障碍

Huihui Shi1, Lei Chen2, Juan Huang3

  • 1Department of Gastroenterology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai, 200090, China.

Oncology research
|January 8, 2026
PubMed
概括

富含氨酸/氨酸的核蛋白1 (CSRNP1) 在肝细胞癌 (HCC) 中起到瘤抑制作用. 它的过度表达会诱导氧化应激,并激活JNK/p38 MAPK通路,这表明CSRNP1是HCC.的潜在治疗标.

关键词:
富含氨酸/氨酸的核蛋白 1 1c-Jun N-终端酶/p38 中原激活蛋白酶通路肝细胞癌是肝细胞癌.线粒体功能障碍 线粒体功能障碍反应性氧物种的积累反应性氧物种的积累.

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