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Updated: Jan 13, 2026

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在一个单一的实验室环境中构建一个精确的预测模型来选儿童生长激素缺乏症:使用血清IGF-1与年龄的比率作为一个有希望的预测标记

Shichao Qiu1, Ting Zhao1, Yihua Lian1

  • 1Department of Endocrinology, Genetics and Metabolism, Xi'an Children's Hospital, Xi'an, China.

Translational pediatrics
|January 8, 2026
PubMed
概括

IGF-1/年龄比率显示出作为儿童生长激素缺乏症 (GHD) 查工具的希望. 这种标记可以帮助识别可能需要进一步测试的儿童,提高诊断效率.

关键词:
生长激素缺乏症 (GHD) 是一种生物标志物 生物标志物类似胰岛素的增长因子1 (IGF-1)胰岛素类生长因子结合蛋白3 (IGFBP-3)预测模型 预测模型

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Glomerular filtration rate (GFR) can be estimated from serum creatinine using the modification of diet in renal disease (MDRD) formula or the chronic kidney disease–epidemiology collaboration (CKD–EPI) equation. Both methods are widely used in clinical practice to assess kidney function and guide treatment decisions.The MDRD equation does not require weight or height measurements and is normalized to the body surface area of 1.73 m², considered the average adult surface area.
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