在患有威普尔病的免疫抑制患者中,非典型的迁移性状视网膜病变
Shivesh Shah1, Frida Velcani1, Emily S Levine2
1Geisel School of Medicine at Dartmouth, Hanover, NH.
ACG case reports journal
|January 8, 2026
概括
威普尔病是一种罕见的细菌感染,可以引起异常的眼睛炎症. 这一案例突显了免疫功能受损患者出现异常眼部症状的诊断挑战.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 惠普尔病是一种罕见的系统性细菌感染,由Tropheryma whipplei引起.
- 眼部卷入是惠普尔病的一种不常见的表现,影响眼部前后两部分.
- 非特定的临床特征往往会延迟诊断.
研究的目的:
- 报告一种非典型的眼部呈现的惠普尔病病例.
- 为了强调免疫受损患者的诊断挑战.
- 强调在无法解释的眼睛炎症中考虑惠普尔病的重要性.
主要方法:
- 一个70岁的免疫力受损的男性患者的病例报告.
- 单边眼部炎症的临床表现,包括hypopyon,炎和视网膜病变.
- 诊断工作包括内抗菌疗法和十二指肠活检.
主要成果:
- 患者出现了严重的单侧眼炎,对初始治疗没有反应.
- 系统性症状和十二指肠活检结果在眼部呈现四个月后证实了惠普尔病.
- 该病例显示出一种非典型的表现,没有经典的胃肠道症状.
结论:
- 眼部炎症可能是威普尔病的早期或唯一表现,特别是在免疫受损的个体.
- 由于异常表现和缺乏胃肠道症状,诊断延迟很常见.
- 在这种情况下,增加临床怀疑和彻底调查对于诊断惠普尔病至关重要.
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