身体活动对卵巢反应的影响:在体外受精患者中的前性研究
Fatima Olaso1, Rosario Mendoza1, Iñaki Echeverria2
1Obstetrics and Gynecology Department, Human Reproduction Unit, Cruces University Hospital, Barakaldo, ESP.
Cureus
|January 8, 2026
概括
定期的体力活动 (PA) 通常不会影响在体外受精 (IVF) 周期中的卵巢反应. 然而,高PA可能会改善卵子细胞产量在女性内膜异位症,排卵障碍,或正常的BMI.
科学领域:
- 生殖内分泌学和不孕症研究.
- 运动生理学及其对生殖健康的影响.
背景情况:
- 众所周知,体力活动 (PA) 对整体健康有益,但其对辅助生殖成功的影响尚不清楚.
- 关于不同程度的体力活动与体外受精 (IVF) 或细胞内精子注射 (ICSI) 周期的结果之间的关联没有确立的共识.
研究的目的:
- 研究不同体力活动水平对IVF/ICSI周期中卵巢对受控刺激的反应的影响.
- 要确定身体活动是否会影响提取和成熟卵细胞的数量.
主要方法:
- 一项前性观察性研究,涉及617名接受试管婴儿/ICSI周期的妇女.
- 使用国际体力活动问卷 (IPAQ) 和三轴加速度计来评估体力活动.
- 患者被分为低,中等和高体力活动组.
主要成果:
- 总的来说,根据IPAQ,在低,中等和高体力活动组中没有观察到提取或成熟卵细胞数量的显著差异.
- 加速度计数据也显示,身体活动组之间的卵巢反应没有全球显著差异.
- 在特定的子组中,高和中等体力活动与患有子宫内膜异位症 (p=0.024) 和排卵障碍 (p=0.038) 的女性中更成熟的卵细胞有关.
- 高度体力活动与正常BMI (p=0.005,p=0.004) 的女性中收集和成熟的卵细胞数量较多有关.
结论:
- 在全球范围内,体力活动水平似乎不会影响IVF周期期间检索和成熟卵细胞的卵巢反应.
- 然而,在特定的患者亚组中,较高的体力活动水平可能与卵巢反应的改善有关,包括患有子宫内膜异位症,排卵障碍和正常BMI的患者.
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