扩大内镜内外科手术后的临时鼻发病,用于骨底部瘤
Lidia Dennis Chiramal1, Rajan Sundarasan1, Ari G Chacko2
1Department of ENT, Christian Medical College, Vellore, Tamil Nadu, India.
Journal of neurological surgery. Part B, Skull base
|January 8, 2026
概括
扩展的内镜内鼻腔方法会导致暂时的嗅觉丧失和鼻子问题. 虽然大多数患者康复了,但有些人经历了轻微的持续性嗅觉功能障碍和手术后生活质量下降.
科学领域:
- 神经外科 神经外科
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 头骨底部手术 头骨底部手术
背景情况:
- 头骨底部瘤通常需要复杂的手术干预.
- 扩展内镜内腔方法 (EEA) 提供了对骨底部病变的最小侵入性访问.
- 评估EEA对嗅觉功能和生活质量 (QOL) 的影响对于患者的治疗结果至关重要.
研究的目的:
- 为了评估头骨底部瘤的EEA患者的嗅觉功能障碍和QOL.
- 确定EEA对嗅觉和鼻子健康的短期和中期影响.
主要方法:
- 一项前性观察性研究,涉及29名患者接受前骨底和脑垂体病变的EEA.
- 使用康涅狄格州化学感官临床研究中心的嗅觉测试来评估嗅觉功能.
- 使用中鼻结局测试22 (SNOT-22) 问卷来评估QOL.
- 术前和术后2周和3个月进行的评估.
主要成果:
- 与手术前基线相比,术后2周嗅觉得分明显恶化.
- 3个月后,48%的患者恢复了基线的嗅觉,48%的患者有轻度低血,1个患者有中度低血.
- 术后立即QOL得分显著下降,在3个月后出现改善,但没有达到手术前水平.
结论:
- 前底瘤的EEA导致过渡性嗅觉功能障碍和鼻腔发病率.
- 虽然大多数患者经历了改善,但大约50%的患者在3个月后可能有轻微的残留嗅觉功能障碍.
- 嗅觉上皮质保护技术,术后鼻腔护理和淋浴可以改善嗅觉结果.
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