在科学范式下的人工智能下,在生物学和医学中大语言模型的创新应用
Xing-Li Cun1,2, Chen-Jun Ding2, Fang Chen2,3
1Research and Consulting Center for The Frontier of the Intersection of Biotechnology and Information Technology(BT-IT),Chinese Academy of Sciences, Chengdu 610299,China.
概括
大型语言模型 (LLM) 正在彻底改变生物医学研究,为了解复杂疾病和推进精准医学提供了新的方法. 本综述探讨了LLM应用,挑战和科学人工智能的快速发展领域的未来方向.
科学领域:
- 生物医学研究的研究.
- 医学中的人工智能
- 计算生物学是一种计算生物学.
背景情况:
- 科学范式的人工智能正在快速发展,大型语言模型 (LLM) 成为一种变革性技术.
- 法律学正在越来越多地影响生物和医学研究,需要对其应用进行系统的审查.
- 了解LLM的作用对于破译复杂疾病和推进精准医学的方法创新至关重要.
研究的目的:
- 系统地审查和分析LLMs在生物医学研究中的创新应用.
- 阐明尖端研究进展,发展轨迹和LLM应用的持续挑战.
- 为该领域的方法创新和研究范式转型提供关键参考.
主要方法:
- 对过去两年的高影响力同行评审出版物和预印稿进行比较分析.
- 系统检查跨生物和医学领域的LLM应用程序.
- 审查研究进展,发展轨迹和挑战.
主要成果:
- 在生物学和医学领域的LLM应用中识别尖端研究进展和发展轨迹.
- 阐明当前LLM应用中持续存在的挑战和局限性.
- 概述LLMs为生物医学研究注入的变革动力.
结论:
- 在科学范式中,LLM代表了人工智能的重大进步,为生物医学发现提供了新的途径.
- 解决跨学科挑战和未来考虑对于充分利用法学士的潜力至关重要.
- 该领域正在迅速发展,有望在理解复杂疾病和推进精准医学方面进一步转变.
相关概念视频
Microorganisms in Medicine and Therapeutics
928
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
928
Synthetic Biology
5.5K
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
Golden rice
Golden rice is a genetically modified...
5.5K
Issues And Trends In Healthcare Delivery System
6.1K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
6.1K
The Central Dogma
31.8K
The central dogma explains the flow of genetic information from DNA nucleotides to the amino acid sequence of proteins.
RNA is the Missing Link Between DNA and Proteins
In the early 1900s, scientists discovered that DNA stores all the information needed for cellular functions and that proteins perform most of these functions. However, the mechanisms of converting genetic information into functional proteins remained unknown for many years. Initially, it was believed that a single gene is...
RNA is the Missing Link Between DNA and Proteins
In the early 1900s, scientists discovered that DNA stores all the information needed for cellular functions and that proteins perform most of these functions. However, the mechanisms of converting genetic information into functional proteins remained unknown for many years. Initially, it was believed that a single gene is...
31.8K


