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维生素B合成的基因及其在微生物生产者中的分布

Yan Wang^1,2, Yitian Yu², Nuohan Xu¹

¹Institute for Advanced Study, Shaoxing University, Shaoxing 312000, P. R. of China.

Journal of agricultural and food chemistry

|January 8, 2026

概括

微生物在不同的环境中产生必需的B族维生素 (VBs). 这项研究绘制了VB生产者的地图,揭示了土壤和淡水息地富含VB合成,对农业和生物技术有影响.

科学领域:

微生物学微生物学
转基因组学是指转基因组学.
生物地质化学生物地质化学

背景情况:

维生素B (VBs) 是生命所必需的微量营养素.
微生物对自然环境中维生素B生产的贡献在很大程度上是未知的.
了解VB合成对于生态和生物技术应用至关重要.

研究的目的:

将维生素B生产者的全球分布映射到各种息地.
识别参与维生素B合成的基因及其环境驱动因素.
创建一个关于微生物VB合成途径的全面数据库.

主要方法:

对126,931个元基因组组装基因组的分析.
建立一个数据库,对87个B族维生素合成基因进行分类.
对VB生产者和VB独立生物体的生物信息识别.
环境因素与VB生产潜力之间的相关性分析.

主要成果:

土壤和淡水息地显示出B族维生素生产者的最大多样性 (VB₁,VB₂,VB₇,VB₉,VB₁₂).
对VB₅的生物合成能力是罕见的,对VB₃和VB₆是有限的.
玛蛋白细菌是关键的生产者,能够合成多达八种VB类型.
土壤的硫含量和导电性与VB生产潜力有正相关.
实验验证证证实了Acinetobacter kookii*中的VB₃和VB₇合成.

结论:

这项研究提供了一个基本的基因数据库和微生物B族维生素生产的预测框架.
确定的VB生产者跨越有益的和致病的种类,需要仔细考虑.
研究结果将微生物VB合成与土壤健康联系起来,并为农业和生物技术的进步提供了潜力.

关键词:

VB的生产者是VB的生产者有益细菌是一种有益的细菌.隐藏的马尔科夫模型致病性细菌是一种致病性细菌.维生素B合成基因的基因

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