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Updated: Jan 13, 2026

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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探索携带伊米达佐利丁环的新西米卡巴兹基衍生物作为潜在的抗菌剂:设计,合成和分子动力学研究

Faika Başoğlu1,2, Merve Ataman3, Fatih Tok4

  • 1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Near East University, Mersin, Türkiye.

Chemistry & biodiversity
|January 8, 2026
PubMed
概括

研究人员合成了新的 thiosemicarbazide 衍生物以准细菌和真菌细胞壁. 化合物3,14,和9分别表现出显著的抗微生物和抗真菌活性,而化合物9与外-β-(1,3) - 葡萄糖酶结合.

关键词:
模拟MD的模拟方法抗微生物药物是一种抗菌药物.它们是 exo-β-(1,3) - 葡萄糖酶.这种类型的二氧化基化.

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