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Updated: Jan 13, 2026

Drug-Induced Senescence in Liver Cells Promotes M2 Macrophage Polarization: Implications for Tyrosine Kinase Inhibitor-Associated Hepatotoxicity
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m1A-依赖的TRMT6/61A-ARG2轴通过重塑瘤微环境来驱动原原老化

Tuoyang Li1,2,3,4,5, Mingzhe Huang1,2,3,4,5, Jinlin Cai1,2,3,4

  • 1Department of General Surgery (Colorectal Surgery), The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|January 8, 2026
PubMed
概括

细胞衰老通过与衰老相关的分泌表型 (SASP) 驱动癌症. 这项研究揭示了TRMT6/TRMT61A复合体通过增强特定蛋白质的翻译来驱动结直肠癌中的原瘤性SASP.

关键词:
结肠直肠癌是什么意思m1A1A 在线观看衰老相关的分泌体现型衰老的瘤细胞.瘤微环境是一个微环境.

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